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WRAL News story on Forest
"Imagine you've just had a baby only to have doctors tell you there's a 70% chance he or she will die."

Pediatric Database - Omenn Disease
"An immunodeficiency disorder of both T- and B-cells characterized by recurrent infections, typical skin eruptions, and eosinophilia. "

The Who Report on Primary Immunodeficiency Diseases
INTRODUCTION - The first barriers to infection are the skin and mucous membranes, and the substances they secrete.

SCID Homepage
SCID is a primary immune deficiency. The defining characteristic is usually a severe defect in both the T- & B-lymphocyte systems.

Primary Immune Deficiency Webring
The PID Webring is designed to help those looking for information on any of the Primary Immune Deficiencies find relevant web sites. 

Children's Organ Transplant Association
COTA's primary mission is to ensure that no U.S. citizen is ever denied a life-saving transplant or access to a transplant waiting list, due solely to the lack of funds. Our secondary focus is to promote organ donations and to provide public education on all aspects of the organ donation process.

The First Family Pledge
Transplantation of organs and tissue has become one of the most remarkable success stories in medicine, now giving tens of thousands of desperately ill Americans each year a new chance at life — and returning them to the love of their families.  

First Family Pledge Congress, April 14th
More than 200 transplant kids from all 50 states, ranging in age from 2 to 9, will be flying into Washington on April 14th for the First Family Pledge Congress on Organ and Tissue Donation, where they will publicly thank Members of Congress from their state for demonstrating leadership in supporting the First Family Pledge organ and tissue donation initiative. 
The Kentucky Page Forest Madden, 4 Richmond, KY

American Society of Transplant Surgeons - News and Media A four-year-old Richmond boy, who is alive today because of a bone transplant, wants to thank Members of Congress committed to supporting organ and tissue donation.

OMIM # 603554
RETICULOENDOTHELIOSIS, FAMILIAL, WITH EOSINOPHILIA
SEVERE COMBINED IMMUNODEFICIENCY WITH HYPEREOSINOPHILIA

OMIM # 179615
RECOMBINATION ACTIVATING GENE 1; RAG1

OMIM # 179616
RECOMBINATION ACTIVATING GENE 2; RAG2

PubMed - Partial V(D)J recombination activity leads to Omenn syndrome
Genomic rearrangement of the antigen receptor loci is initiated by the two lymphoid-specific proteins Rag-1 and Rag-2.

Human Genome and Multifactor Deseases Primary Immunodeficiency Unit
by Dr. Anna Villa

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This page last updated 09/20/05